How do you go about avoiding becoming infected by a harmful airborne virus like COVID-19 -- especially if you're a student heading back to campus? There are, of course, a number of blindingly obvious ways to do this. However, because so many people seem to have forgotten them, I thought it worth p
Tylenol and Hangovers: A Dangerous Mix?
Acetaminophen -- the active ingredient in Tylenol -- is bad news for your liver if you take too much of it. The same is true for alcohol. So should you avoid popping Tylenol to take the edge off the morning-after hangover? Probably yes -- although the biology behind how the two substances interact is more complex than you might imagine. FURTHER RESOURCES Medline Plus: Trusted Health Information for You. Acetaminophen. U.S. National Library of Medicine, National Institute of Health. AHFS Consumer Medication Information. Revised: 15 August 2013. Accessed online: 27 September 2013. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a681004.html FDA information on acetaminophen toxicity: http://www.fda.gov/Drugs/DrugSafety/SafeUseInitiative/ucm230396.htm Mayo Clinic: Acetaminophen and Children: Why Dose Matters: http://www.mayoclinic.com/health/acetaminophen/HO00002 Pro Publica report on acetaminophen risks: http://www.propublica.org/article/tylenol-mcneil-fda-use-only-as-directed L.E. Schmidt, K Dalhoff, H.E. Poulson. Acute versus chronic alcohol consumption in acetaminophen-induced hepatotoxicity. Hepatology (32) 2002; p.876-882. http://www.ncbi.nlm.nih.gov/pubmed/11915034 F. Yang, D. A. Beard. Thermodynamically based profiling of drug metabolism and drug-drug metabolic interactions: A case study of acetaminophen and ethanol toxic interactions. Biophysical Chemistry, 120 (2) p. 121-134. 20 March 2006. Accessed online: 27 September 2013. http://dx.doi.org/10.1016/j.bpc.2005.10.013 P. Zhao, T.K. Kalhourn, J.T. Slattery. Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rats. Hepatology (36); p. 326-335. 2002. K. Thummel, et al. Ethanol and production of hepatotoxic metabolite of acetaminophen in healthy adults. Clinical Pharmacology and Therapeutics (2000) 67; p. 591-599. http://dx.doi.org/10.1067/mcp.2000.106574 THIS WEEK'S RISK BITES TEAM: Producer: Andrew Maynard Research Director: David Faulkner Background Research: Alyssa berry Risk Bites is your guide to making sense of risk. We cover everything from understanding and balancing the risks and benefits of everyday products, to health science more broadly, to the potential impacts of emerging technologies, to making sense of risk perception. If you enjoy our videos, please subscribe, and spread the word! Click here to see more videos: https://alugha.com/RiskBites
More videos by this producer
What is solution-focused risk assessment, and how can it help in the governance of emerging technologies? Solution-focused risk assessment, or SFRA, is a novel way of thinking about and managing risks developed by Adam Finkel. It involves analyzing the good and bad consequences of what we can do to
What epidemiology is, and why it's important? Risk Bites provides a simple introduction to what epidemiology is, and how to make sense of epidemiology studies when people's health is on the line. With Mariya Voytyuk. Written, illustrated, narrated and filmed by Dr. Mariya Voytyuk RISK BITES Risk